The science and research behind IQOS. 

Our scientific assessment journey.


Scientific programme.

We have developed a comprehensive step-by-step scientific assessment programme. This programme is inspired by the practices of the pharmaceutical industry and is in line with the USA’s Federal Drug Administration’s 2012 guidance on the assessment of candidate Modified Risk Tobacco products. Our assessment was also conducted according to international standards.

Long term studies.

Once IQOS is available in the market, the research moves from being conducted in a pre-market setting to a real-world post-market setting.  There, we look at how the product is being used and by whom in order to complement our pre-market findings and to do our best to identify and prevent use or uptake by unintended audiences. After years of commercialisation in many countries, the available data confirms our pre-market observations, in particular in terms of IQOS’ appeal to adult smokers and the relative lack of interest in former and never smokers.

We also monitor reports of health effects now that the product is used by millions of adult users. Long-term studies will eventually help us to evaluate the potential disease–specific risk reduction of IQOS. Gathering data to answer this question takes time, but it’s the right choice. So far, all the data we’ve seen points in the right direction.

The Result

IQOS is a better choice than continued smoking. The totality of scientific evidence available to-date clearly demonstrates that switching completely to IQOS presents less risk to your health than continuing to smoke cigarettes.*

IQOS is not risk-free and delivers nicotine, which is addictive. The best decision any smoker can make is to quit tobacco and nicotine use altogether.

*Source: Based on the totality of evidence available for IQOS in comparison with continuing to smoke, which includes data on aerosol chemistry from 10 clinical studies conducted with thousands of participants in the US, Japan and Poland, and data from 18 non-clinical studies.